In this Biocoillider episode, Adam Zaretsky talks with Matej Vakula about multi-species collaborations in bioart. What does it mean to ask for permission, and how do we ask non-humans? Can language or training influence gene expression? What ideas truly underpin the aesthetics of transhuman enhancement? What does the hype around certain scientific discoveries–such as CRISPR–serve? These questions are only a few excerpts from the range of topics we discussed.